Product details
Background:
Antizyme inhibitor 1 rabbit pAb
Ucallm_WP6205-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AZIN1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 49kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Antizyme inhibitor 1 |
| Specificity | This antibody detects endogenous levels of Antizyme inhibitor 1 at Human, Mouse,Rat |
| Gene Name | AZIN1 OAZI OAZIN |
| Protein Name | Antizyme inhibitor 1 (AZI) (Ornithine decarboxylase antizyme inhibitor) |
| Other Name | |
| Species | Human |
| Gene ID | 51582 |
| Uniprot | O14977, |
| Species.1 | Mouse |
| Gene ID.1 | 54375 |
| Uniprot.1 | O35484, |
| Species.2 | Rat |
| Gene ID.2 | 58961 |
| Uniprot.2 | Q63764 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding . Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production . |
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