Product details
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FAAH rabbit pAb
Ucallm_WP6610-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FAAH |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 64kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FAAH |
| Specificity | This antibody detects endogenous levels of FAAH at Human, Mouse,Rat |
| Gene Name | FAAH FAAH1 |
| Protein Name | Fatty-acid amide hydrolase 1 (Anandamide amidohydrolase 1) (Oleamide hydrolase 1) |
| Other Name | |
| Species | Human |
| Gene ID | 2166 |
| Uniprot | O00519, |
| Species.1 | Mouse |
| Gene ID.1 | 14073 |
| Uniprot.1 | O08914, |
| Species.2 | Rat |
| Gene ID.2 | 100911581 |
| Uniprot.2 | P97612 |
| Cellular Localization | Endomembrane system; Single-pass membrane protein . Cytoplasm, cytoskeleton . Seems to be attached to intracellular membranes and a portion of the cytoskeletal network. |
| Tissue Expression | Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules . Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates . It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol) . FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids (By similarity). |
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