Price range: $268.00 through $328.00
Background:
This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | FACE2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | FACE2 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RCE1 FACE2 RCE1A RCE1B |
| Protein Name | CAAX prenyl protease 2 (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1) |
| Other Name | |
| Species | Human |
| Gene ID | 9986 |
| Uniprot | Q9Y256, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P57791, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | B0BMW8 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | >>Terpenoid backbone biosynthesis |
| Function | Function:Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1.,similarity:Belongs to the peptidase U48 family.,tissue specificity:Ubiquitous., |
