Product details
Background:
WDR18 rabbit pAb
Ucallm_WP6680-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | WDR18 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 48kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human WDR18 |
| Specificity | This antibody detects endogenous levels of WDR18 at Human, Mouse,Rat |
| Gene Name | WDR18 |
| Protein Name | WD repeat-containing protein 18 |
| Other Name | |
| Species | Human |
| Gene ID | 57418 |
| Uniprot | Q9BV38, |
| Species.1 | Mouse |
| Gene ID.1 | 216156 |
| Uniprot.1 | Q4VBE8, |
| Species.2 | Rat |
| Gene ID.2 | 314617 |
| Uniprot.2 | Q499N3 |
| Cellular Localization | Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Dynein axonemal particle . Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes . Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit . May play a role during development (By similarity). |
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