SKU: WP6713 Categories: ,

C7orf30 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6713-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetMALSU1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)26kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human C7orf30
SpecificityThis antibody detects endogenous levels of C7orf30 at Human, Mouse
Gene NameMALSU1 C7orf30
Protein NameMitochondrial assembly of ribosomal large subunit protein 1
Other Name
SpeciesHuman
Gene ID115416
UniprotQ96EH3,
Species.1Mouse
Gene ID.175593
Uniprot.1Q9CWV0
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion matrix . Colocalizes with MRPL12 and/or MRPL14. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionRequired for normal mitochondrial ribosome function and mitochondrial translation . May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome . May function as a ribosomal silencing factor (Probable).
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