Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C7orf30
Specificity
This antibody detects endogenous levels of C7orf30 at Human, Mouse
Gene Name
MALSU1 C7orf30
Protein Name
Mitochondrial assembly of ribosomal large subunit protein 1
Other Name
Species
Human
Gene ID
115416
Uniprot
Q96EH3,
Species.1
Mouse
Gene ID.1
75593
Uniprot.1
Q9CWV0
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Mitochondrion matrix . Colocalizes with MRPL12 and/or MRPL14. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Required for normal mitochondrial ribosome function and mitochondrial translation . May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome . May function as a ribosomal silencing factor (Probable).