Product details
Background:
ARCN1 rabbit pAb
Ucallm_WP6985-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ARCN1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 56kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARCN1 |
| Specificity | This antibody detects endogenous levels of ARCN1 at Human, Mouse,Rat |
| Gene Name | ARCN1 COPD |
| Protein Name | Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP) |
| Other Name | |
| Species | Human |
| Gene ID | 372 |
| Uniprot | P48444, |
| Species.1 | Mouse |
| Gene ID.1 | 213827 |
| Uniprot.1 | Q5XJY5, |
| Species.2 | Rat |
| Gene ID.2 | 300674 |
| Uniprot.2 | Q66H80 |
| Cellular Localization | Cytoplasm . Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side . The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. . |
| Tissue Expression | Ubiquitously expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the coatomer, a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). |
Please login to post questions
Related products
