Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ALX1
Specificity
This antibody detects endogenous levels of ALX1 at Human, Mouse,Rat
Gene Name
ALX1 CART1
Protein Name
ALX homeobox protein 1 (Cartilage homeoprotein 1) (CART-1)
Other Name
Species
Human
Gene ID
8092
Uniprot
Q15699,
Species.1
Mouse
Gene ID.1
216285
Uniprot.1
Q8C8B0,
Species.2
Rat
Gene ID.2
25401
Uniprot.2
Q63087
Cellular Localization
Nucleus .
Tissue Expression
Cartilage and cervix tissue.
Signaling_pathway
Research Areas
Function
Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes . Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival . May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1 .