Product details
Background:
UBE2F rabbit pAb
Ucallm_WP7508-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | UBE2F |
| Reactivity | Human, Rat |
| Applications | WB |
| MW(Calculated) | 20kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human UBE2F |
| Specificity | This antibody detects endogenous levels of UBE2F at Human,Rat |
| Gene Name | UBE2F NCE2 |
| Protein Name | NEDD8-conjugating enzyme UBE2F (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (Ubiquitin-conjugating enzyme E2 F) |
| Other Name | |
| Species | Human |
| Gene ID | 140739 |
| Uniprot | Q969M7, |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | 363284 |
| Uniprot.2 | Q5U203 |
| Cellular Localization | |
| Tissue Expression | Widely expressed (at protein level). |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> Ubiquitin mediated proteolysis |
| Research Areas | |
| Function | Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. |
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