Product details
Background:
VASH2 rabbit pAb
Ucallm_WP7948-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | VASH2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 39kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human VASH2 |
| Specificity | This antibody detects endogenous levels of VASH2 at Human, Mouse |
| Gene Name | VASH2 VASHL |
| Protein Name | Vasohibin-2 (Vasohibin-like protein) |
| Other Name | |
| Species | Human |
| Gene ID | 79805 |
| Uniprot | Q86V25, |
| Species.1 | Mouse |
| Gene ID.1 | 226841 |
| Uniprot.1 | Q8C5G2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Secreted . Cytoplasm, cytoskeleton . Mainly localizes in the cytoplasm (PubMed:19204325). Some fraction is secreted via a non-canonical secretion system; interaction with SVBP promotes secretion (PubMed:20736312). Associates with microtubules (PubMed:31235911). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function . Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning . Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis . Plays a role in axon formation . |
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