Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TDRD5
Specificity
This antibody detects endogenous levels of TDRD5 at Human, Mouse,Rat
Gene Name
TDRD5
Protein Name
Tudor domain-containing protein 5
Other Name
Species
Human
Gene ID
163589
Uniprot
Q8NAT2,
Species.1
Mouse
Gene ID.1
214575
Uniprot.1
Q5VCS6,
Species.2
Rat
Gene ID.2
289129
Uniprot.2
B4F7C4
Cellular Localization
Cytoplasm . Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity).