SKU: WP8259 Categories: ,

SPAM1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8259-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetSPAM1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)56kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SPAM1
SpecificityThis antibody detects endogenous levels of SPAM1 at Human, Mouse,Rat
Gene NameSPAM1 HYAL3 PH20
Protein NameHyaluronidase PH-20 (Hyal-PH20) (Hyaluronoglucosaminidase PH-20) (Sperm adhesion molecule 1) (Sperm surface protein PH-20)
Other NameSPAM1; / HYAL3; / PH20; / Hyaluronidase PH-20; / Hyal-PH20; / Hyaluronoglucosaminidase PH-20; / Sperm adhesion molecule 1; / Sperm surface protein PH-20
SpeciesHuman
Gene ID6677
UniprotP38567,
Species.1Mouse
Gene ID.120690
Uniprot.1P48794,
Species.2Rat
Gene ID.2117037
Uniprot.2Q62803
Cellular LocalizationCell membrane; Lipid-anchor, GPI-anchor.
Tissue ExpressionTestis.
Signaling_pathwayCellular Processes >> Transport and catabolism >> Lysosome
Research Areas
FunctionInvolved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
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