Product details
Background:
VPS13A rabbit pAb
Ucallm_WP8469-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | VPS13A |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 349kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human VPS13A |
| Specificity | This antibody detects endogenous levels of VPS13A at Human, Mouse |
| Gene Name | VPS13A CHAC KIAA0986 |
| Protein Name | Vacuolar protein sorting-associated protein 13A (Chorea-acanthocytosis protein) (Chorein) |
| Other Name | |
| Species | Human |
| Gene ID | 23230 |
| Uniprot | Q96RL7, |
| Species.1 | Mouse |
| Gene ID.1 | 271564 |
| Uniprot.1 | Q5H8C4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion outer membrane; Peripheral membrane protein . Endoplasmic reticulum membrane; Peripheral membrane protein . Endosome membrane; Peripheral membrane protein . Lysosome membrane; Peripheral membrane protein . Lipid droplet . Golgi apparatus . Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle . Localizes at mitochondria-endosomes and mitochondria-endoplasmic reticulum contact sites (PubMed:30741634, PubMed:30709847, PubMed:30093493). . |
| Tissue Expression | Expressed in red blood cells (at protein level) (PubMed:31086825). Widely expressed, with high expression in brain, heart, skeletal muscle and kidney (PubMed:15498460). |
| Signaling_pathway | |
| Research Areas | |
| Function | Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phospholipids . Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria . Negatively regulates lipid droplet size and motility . Required for efficient lysosomal protein degradation . |
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