Product details
Background:
JP45/JSRP1 rabbit pAb
Ucallm_WP8481-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | JSRP1 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 36kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human JP45/JSRP1 |
| Specificity | This antibody detects endogenous levels of JP45/JSRP1 at Human |
| Gene Name | JSRP1 JP45 |
| Protein Name | Junctional sarcoplasmic reticulum protein 1 (Junctional-face membrane protein of 45 kDa homolog) (JP-45) |
| Other Name | |
| Species | Human |
| Gene ID | 126306 |
| Uniprot | Q96MG2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q3MI48 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Sarcoplasmic reticulum membrane . Endoplasmic reticulum membrane . Colocalizes with ryanodine receptors at the sarcoplasmic reticulum triad membranes. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage-sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity. |
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