Product details
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MED6 rabbit pAb
Ucallm_WP8568-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MED6 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 27kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MED6 |
| Specificity | This antibody detects endogenous levels of MED6 at Human, Mouse |
| Gene Name | MED6 ARC33 |
| Protein Name | Mediator of RNA polymerase II transcription subunit 6 (Activator-recruited cofactor 33 kDa component) (ARC33) (Mediator complex subunit 6) (hMed6) (Renal carcinoma antigen NY-REN-28) |
| Other Name | |
| Species | Human |
| Gene ID | 10001 |
| Uniprot | O75586, |
| Species.1 | Mouse |
| Gene ID.1 | 69792 |
| Uniprot.1 | Q921D4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
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