Product details
Background:
- Please choose product options by visiting SNX4 Polyclonal Antibody.
- Please choose product options by visiting SNX17 rabbit pAb.
- Please choose product options by visiting SNRPF rabbit pAb.
- Please choose product options by visiting SNX13 rabbit pAb.
- Please choose product options by visiting SNX11 rabbit pAb.
- Please choose product options by visiting SNX32 rabbit pAb.
SNX18 rabbit pAb
Ucallm_WP8599-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SNX18 |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | 69kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SNX18 |
| Specificity | This antibody detects endogenous levels of SNX18 at Human |
| Gene Name | SNX18 SH3PXD3B SNAG1 |
| Protein Name | Sorting nexin-18 (SH3 and PX domain-containing protein 3B) (Sorting nexin-associated Golgi protein 1) |
| Other Name | |
| Species | Human |
| Gene ID | 112574 |
| Uniprot | Q96RF0, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q91ZR2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endomembrane system; Peripheral membrane protein; Cytoplasmic side . Endosome membrane; Peripheral membrane protein; Cytoplasmic side . Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side . Localized at sites of endocytosis at the cell membrane (PubMed:18411244). Detected on newly formed macropinosomes (PubMed:21048941). Partially colocalized with clathrin and dynamin at the cell membrane (PubMed:20427313). Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation (PubMed:18411244). . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis . Required for efficient progress through mitosis and cytokinesis . Required for normal formation of the cleavage furrow at the end of mitosis . Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis . Plays a role in macropinocytosis . Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation . Stimulates the GTPase activity of DNM2 . Promotes DNM2 location at the plasma membrane . Together with DNM2, involved in autophagosome assembly by regulating trafficking from recycling endosomes of phospholipid scramblase ATG9A . |
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