SKU: WP14535 Categories: ,

SNX4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14535-100
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Product details

Background:

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012],

Specifications

Size50μL/100μL
TargetSNX4
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC
MW(Calculated)
MW(Observed)60kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human SNX4. AA range:191-240
SpecificitySNX4 Polyclonal Antibody detects endogenous levels of SNX4 protein.
Gene NameSNX4
Protein NameSorting nexin-4
Other NameSNX4; / Sorting nexin-4
SpeciesHuman
Gene ID8723
UniprotO95219,
Species.1Mouse
Gene ID.169150
Uniprot.1Q91YJ2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationEarly endosome membrane; Peripheral membrane protein; Cytoplasmic side . Also detected on a juxtanuclear endocytic recycling compartment (ERC). .
Tissue ExpressionLiver,Skin,
Signaling_pathway
Research Areas>>Endocytosis
FunctionFunction:May be involved in several stages of intracellular trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,
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