Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TRIM36
Specificity
This antibody detects endogenous levels of TRIM36 at Human, Mouse
Gene Name
TRIM36 RBCC728 RNF98
Protein Name
E3 ubiquitin-protein ligase TRIM36 (RING finger protein 98) (Tripartite motif-containing protein 36) (Zinc-binding protein Rbcc728)
Other Name
Species
Human
Gene ID
55521
Uniprot
Q9NQ86,
Species.1
Mouse
Gene ID.1
28105
Uniprot.1
Q80WG7
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Cytoplasmic vesicle, secretory vesicle, acrosome . Cytoplasm, cytoskeleton . Found in the acrosomal region of elongated spermatids and mature sperm. .
Tissue Expression
Highly expressed in testis, prostate and brain (PubMed:15145053). Weakly expressed in kidney, lung and heart (PubMed:15145053). Expressed in fetal tissues (PubMed:28087737).
Signaling_pathway
Research Areas
Function
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation . May play a role in the acrosome reaction and fertilization.