Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human VPS13C
Specificity
This antibody detects endogenous levels of VPS13C at Human, Mouse
Gene Name
VPS13C KIAA1421
Protein Name
Vacuolar protein sorting-associated protein 13C
Other Name
Species
Human
Gene ID
54832
Uniprot
Q709C8,
Species.1
Mouse
Gene ID.1
320528
Uniprot.1
Q8BX70
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Mitochondrion outer membrane . Lipid droplet . Endoplasmic reticulum membrane . Lysosome membrane . Late endosome membrane . May localize to endoplasmic reticulum-endolysosome contact sites. .
Tissue Expression
Widely expressed.
Signaling_pathway
Research Areas
Function
Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential . Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization .