Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SNRPF
Specificity
This antibody detects endogenous levels of SNRPF at Human, Mouse
Gene Name
SNRPF PBSCF
Protein Name
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Other Name
Species
Human
Gene ID
6636
Uniprot
P62306,
Species.1
Mouse
Gene ID.1
69878
Uniprot.1
P62307
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytosol . Nucleus . SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome . Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes . Is also a component of the minor U12 spliceosome . As part of the U7 snRNP it is involved in histone 3'-end processing .