SKU: WP12086 Categories: ,

Dynein LC 2B Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12086-100
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Product details

Background:

function:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport., miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients., similarity:Belongs to the GAMAD family., tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.,

Specifications

Size50μL/100μL
TargetDynein LC 2B
ReactivityHuman, Mouse
ApplicationsIHC, IF, ELISA
MW(Calculated)11kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human DYNLRB2. AA range:21-70
SpecificityDynein LC 2B Polyclonal Antibody detects endogenous levels of Dynein LC 2B protein.
Gene NameDYNLRB2
Protein NameDynein light chain roadblock-type 2
Other NameDYNLRB2; / DNCL2B; / DNLC2B; / ROBLD2; / Dynein light chain roadblock-type 2; / Dynein light chain 2B; / cytoplasmic; / Roadblock domain-containing protein 2
SpeciesHuman
Gene ID83657
UniprotQ8TF09,
Species.1Mouse
Gene ID.175465
Uniprot.1Q9DAJ5
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton.
Tissue ExpressionHigh expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.
Signaling_pathway
Research Areas>>Salmonella infection
FunctionFunction:May be involved in assembly and motor function of dynein, which plays a central role in cell division and intracellular transport.,miscellaneous:Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.,similarity:Belongs to the GAMAD family.,tissue specificity:High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.,
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