SKU: WP12857 Categories: ,

IP6K2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12857-100
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Product details

Background:

This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetIP6K2
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)49kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human IP6K2. AA range:161-210
SpecificityIP6K2 Polyclonal Antibody detects endogenous levels of IP6K2 protein.
Gene NameIP6K2
Protein NameInositol hexakisphosphate kinase 2
Other NameIP6K2; / IHPK2; / TCCCIA00113; / Inositol hexakisphosphate kinase 2; / InsP6 kinase 2; / P; / i; / -uptake stimulator; / PiUS
SpeciesHuman
Gene ID51447
UniprotQ9UHH9,
Species.1Mouse
Gene ID.176500
Uniprot.1Q80V72,
Species.2Rat
Gene ID.259268
Uniprot.2Q9R0U1
Cellular LocalizationNucleus .
Tissue ExpressionCaudate nucleus,Glial tumor,Leukemia,Lung,Skin,Uterus,
Signaling_pathway
Research Areas>>Phosphatidylinositol signaling system
FunctionCatalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,Catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,Function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family.,
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