Price range: $268.00 through $328.00
Background:
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | TCF-9 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 80kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GCF. AA range:141-190 |
| Specificity | TCF-9 Polyclonal Antibody detects endogenous levels of TCF-9 protein. |
| Gene Name | GCFC2 |
| Protein Name | GC-rich sequence DNA-binding factor 2 |
| Other Name | GCFC2; / C2orf3; / GCF; / TCF9; / GC-rich sequence DNA-binding factor 2; / GC-rich sequence DNA-binding factor; / Transcription factor 9; / TCF-9 |
| Species | Human |
| Gene ID | 6936 |
| Uniprot | P16383, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BKT3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleoplasm . Nucleus, nucleolus . |
| Tissue Expression | Widely expressed in tissues and cell lines. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.,sequence Caution:Contaminating sequence. The N-terminus matches the 2q37.3 region.,similarity:Belongs to the GCF family.,tissue specificity:Widely expressed in tissues and cell lines., |
