Price range: $268.00 through $328.00
Background:
This gene encodes a colon cancer antigen that was defined by serological analysis of recombinant cDNA expression libraries. The encoded protein is a member of the teashirt C2H2-type zinc-finger protein family and may be involved in transcriptional regulation of developmental processes. Mutations in this gene may be associated with congenital aural atresia syndrome. [provided by RefSeq, Jan 2012],
| Size | 50μL/100μL |
| Target | TSHZ1 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TSH1. AA range:851-900 |
| Specificity | TSHZ1 Polyclonal Antibody detects endogenous levels of TSHZ1 protein. |
| Gene Name | TSHZ1 |
| Protein Name | Teashirt homolog 1 |
| Other Name | TSHZ1; / SDCCAG33; / TSH1; / Teashirt homolog 1; / Antigen NY-CO-33; / Serologically defined colon cancer antigen 33 |
| Species | Human |
| Gene ID | 10194 |
| Uniprot | Q6ZSZ6, |
| Species.1 | Mouse |
| Gene ID.1 | 110796 |
| Uniprot.1 | Q5DTH5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcriptional regulator involved in developmental processes .,similarity:Belongs to the teashirt C2H2-type zinc-finger protein family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 5 C2H2-type zinc fingers., |
