Name: SP-A Polyclonal Antibody
SKU: WP15268
Price: 268 USD
Availability: InStock

SP-A Polyclonal Antibody

Ucallm_WP15268-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP15268-100

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Product details

Background:

This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009],

Specifications

Size	50μL/100μL
Target	SP-A
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	34kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from the Internal region of human SFTPA1/2. AA range:141-190
Specificity	SP-A Polyclonal Antibody detects endogenous levels of SP-A protein.
Gene Name	SFTPA2/SFTPA1
Protein Name	Pulmonary surfactant-associated protein A2/Pulmonary surfactant-associated protein A1
Other Name	SFTPA2; / COLEC5; / PSAP; / SFTP1; / SFTPA; / SFTPA2B; / Pulmonary surfactant-associated protein A2; / PSP-A; / PSPA; / SP-A; / SP-A2; / 35 kDa pulmonary surfactant-associated protein; / Alveolar proteinosis protein; / Collectin-5; / SFTPA1; / COLEC4; / PSAP; / SFTP1; / SFTPA; / SFTPA1B; / Pulmonary surfactant-associated protein A1; / PSP-A; / PSPA; / SP-A; / SP-A1; / 35 kDa pulmonary surfactant-associated protein; / Alveolar proteinosis protein; / Collectin-4
Species	Human
Gene ID	729238
Uniprot	Q8IWL1,
Species.1
Gene ID.1
Uniprot.1
Species.2	Rat
Gene ID.2	24773
Uniprot.2	P08427
Cellular Localization	Secreted . Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.
Tissue Expression
Signaling_pathway	Cellular Processes >> Transport and catabolism >> Phagosome
Research Areas	>>Phagosome; / >>Pertussis
Function	Function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.,miscellaneous:Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).,polymorphism:At least 6 alleles of SFTPA2 are known: 1A, 1A(0), 1A(1), 1A(2), 1A(3) and 1A(4). The sequence shown is that of allele 1A(0).,similarity:Belongs to the SFTPA family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 collagen-like domain.,subunit:Oligomeric complex of 6 set of homotrimers.,

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SP-A Polyclonal Antibody

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SP-A Polyclonal Antibody

Product details

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