Product details
Background:
function:Plays a role in autophagy., similarity:Belongs to the ATG9 family.,
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Atg9a Polyclonal Antibody
Ucallm_WP15733-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | Atg9a |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:10000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic Peptide of Atg9a |
| Specificity | Atg9a Polyclonal Antibody detects endogenous levels of Atg9a |
| Gene Name | ATG9A APG9L1 |
| Protein Name | Atg9a |
| Other Name | ATG9 autophagy related 9 homolog A; / S. cerevisiae |
| Species | Human |
| Gene ID | 79065 |
| Uniprot | Q7Z3C6, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q68FE2, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q5FWU3 |
| Cellular Localization | Preautophagosomal structure membrane; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein . Late endosome membrane; Multi-pass membrane protein . Recycling endosome membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane; Multi-pass membrane protein . Mitochondrion membrane; Multi-pass membrane protein . Mainly localizes to the trans-Golgi network (TGN) and the endosomal system; cycles between them though vesicle trafficking (PubMed:27316455, PubMed:27663665). Export from the TGN to promote formation of autophagosomes is mediated by the AP-4 complex (PubMed:29180427, PubMed:30262884). Under amino acid starvation or rapamycin treatment, redistributes to preautophagosomal structure/phagophore assembly site (PAS) (PubMed:16940348). The starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1 (PubMed:16940348). Upon autophagy induction, a small portion transiently localizes to the autophagic membranes (PubMed:22456507). Recruited to damaged mitochondria during mitophagy in a RIMOC1-dependent manner (PubMed:34432599). . |
| Tissue Expression | Brain,Embryo,Epithelium,Fetal brain,Lung endothelial cell,Lymph,Rectum tumor,Testis |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal;Cellular Processes >> Transport and catabolism >> Mitophagy - animal |
| Research Areas | >>Autophagy - other; / >>Mitophagy - animal; / >>Autophagy - animal |
| Function | Function:Plays a role in autophagy.,similarity:Belongs to the ATG9 family., |
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