Name: CCL17 Polyclonal Antibody
SKU: WP16155
Price: 268 USD
Availability: InStock

CCL17 Polyclonal Antibody

Ucallm_WP16155-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP16155-100

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Product details

Background:

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014],

Specifications

Size	50μL/100μL
Target	TARC
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	10kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA(peptide)1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human CCL17 AA range: 21-70
Specificity	This antibody detects endogenous levels of human CCL17
Gene Name	CCL17 SCYA17 TARC
Protein Name	C-C motif chemokine 17
Other Name	CCL17; / SCYA17; / TARC; / C-C motif chemokine 17; / CC chemokine TARC; / Small-inducible cytokine A17; / Thymus and activation-regulated chemokine
Species	Human
Gene ID	6361
Uniprot	Q92583
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Secreted.
Tissue Expression	Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.
Signaling_pathway	Organismal Systems >> Immune system >> IL-17 signaling pathway;Organismal Systems >> Immune system >> Chemokine signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction;Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Research Areas	>>Cytokine-cytokine receptor interaction; / >>Viral protein interaction with cytokine and cytokine receptor; / >>Chemokine signaling pathway; / >>C-type lectin receptor signaling pathway; / >>IL-17 signaling pathway
Function	Caution:Was originally (PubMed:9521068) thought to be a ligand for CCR8.,Function:Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.,induction:By phytohemagglutinin (PHA) in the peripheral blood mononuclear cells and by cytokines in monocytes.,online information:CCL17 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.,

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CCL17 Polyclonal Antibody

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CCL17 Polyclonal Antibody

Product details

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