SKU: WP10848 Categories: ,

14-3-3 η Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10848-100
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Product details

Background:

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009],

Specifications

Target14-3-3 eta
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)42kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human 14-3-3 eta. AA range:51-100
Sequence
Specificity14-3-3 η Polyclonal Antibody detects endogenous levels of 14-3-3 η protein.
Gene NameYWHAH
Protein Name14-3-3 protein eta
AliasYWHAH;YWHA1;14-3-3 protein eta;Protein AS1
Organism-1Human
Gene ID-17533
SwissProt-1Q04917
Organism-2Mouse
Gene ID-222629
SwissProt-2P68510
Organism-3Rat
Gene ID-325576
SwissProt-3P68511
Organism-4
Gene ID-4
SwissProt-4
Cellular Localizationcytoplasm, mitochondrion, cytosol, plasma membrane, intercalated disc, cytoplasmic vesicle membrane, extracellular exosome,
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