Price range: $268.00 through $328.00
Background:
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013],
| Specification | 50μL;100μL |
| Target | AATM |
| Reactivity | Human, Mouse, Rat, Monkey |
| Applications | WB, IF, ELISA |
| MW(Calculated) | 48kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications. |
| Composition | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification Process | Affinity purification |
| Puity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | |
| Immunogen | Purified recombinant fragment of human AATM expressed in E. Coli. |
| Sequence | |
| Specificity | AATM Monoclonal Antibody detects endogenous levels of AATM protein. |
| Gene Name | GOT2 |
| Protein Name | Aspartate aminotransferase, mitochondrial |
| Alias | GOT2;Aspartate aminotransferase;mitochondrial;mAspAT;Fatty acid-binding protein;FABP-1;Glutamate oxaloacetate transaminase 2;Kynurenine aminotransferase 4;Kynurenine aminotransferase IV;Kynurenine--oxoglutarate transaminase 4;Kynu |
| Organism-1 | Human |
| Gene ID-1 | 2806 |
| SwissProt-1 | P00505 |
| Organism-2 | Mouse |
| Gene ID-2 | 14719 |
| SwissProt-2 | P05202 |
| Organism-3 | Rat |
| Gene ID-3 | 25721 |
| SwissProt-3 | P00507 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Mitochondrion matrix . Cell membrane . Exposure to alcohol promotes translocation to the cell membrane. . |
