SKU: WP10886 Categories: ,

ABCD4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10886-100
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Product details

Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxi

Specifications

TargetABCD4
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)70kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ABCD4. AA range:111-160
Sequence
SpecificityABCD4 Polyclonal Antibody detects endogenous levels of ABCD4 protein.
Gene NameABCD4
Protein NameATP-binding cassette sub-family D member 4
AliasABCD4;PXMP1L;ATP-binding cassette sub-family D member 4;PMP70-related protein;P70R;Peroxisomal membrane protein 1-like;PXMP1-L;Peroxisomal membrane protein 69;PMP69
Organism-1Human
Gene ID-15826
SwissProt-1O14678
Organism-2Mouse
Gene ID-219300
SwissProt-2O89016
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationEndoplasmic reticulum membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Targeted by LMBRD1 lysosomal chaperone to the lysosomal membrane. .
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