SKU: WP10887 Categories: ,

ABCF1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10887-100
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Product details

Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetABCF1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)95kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from ABCF1 . at AA range: 760-840
SpecificityABCF1 Polyclonal Antibody detects endogenous levels of ABCF1 protein.
Gene NameABCF1
Protein NameATP-binding cassette sub-family F member 1
Other NameABCF1; / ABC50; / ATP-binding cassette sub-family F member 1; / ATP-binding cassette 50; / TNF-alpha-stimulated ABC protein
SpeciesHuman
Gene ID23
UniprotQ8NE71,
Species.1Mouse
Gene ID.1224742
Uniprot.1Q6P542,
Species.2Rat
Gene ID.285493
Uniprot.2Q6MG08
Cellular Localization[Isoform 2]: Cytoplasm . Nucleus, nucleoplasm . Nucleus envelope .
Tissue ExpressionUbiquitous.
Signaling_pathway
Research Areas
FunctionFunction:May function in mRNA translation.,induction:By TNF (in cultured synoviocytes).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. EF3 subfamily.,similarity:Contains 2 ABC transporter domains.,subunit:Interacts with eukaryotic initiation factor 2 (eIF2). Associates with the ribosomes.,tissue specificity:Ubiquitous.,
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