Price range: $268.00 through $328.00
Background:
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | ABT1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 30kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ABT1 AA range: 140-190 |
| Specificity | This antibody detects endogenous levels of ABT1 at Human/Mouse/Rat |
| Gene Name | ABT1 |
| Protein Name | ABT1 |
| Other Name | |
| Species | Human |
| Gene ID | 29777 |
| Uniprot | Q9ULW3, |
| Species.1 | Mouse |
| Gene ID.1 | 30946 |
| Uniprot.1 | Q9QYL7, |
| Species.2 | Rat |
| Gene ID.2 | 306960 |
| Uniprot.2 | Q4KLM5 |
| Cellular Localization | Nucleus . Nucleus, nucleolus . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.,similarity:Belongs to the ESF2/ABP1 family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with ESF1/ABTAP., |
