Price range: $268.00 through $328.00
Background:
catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate., function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH., similarity:Belongs to the C/M/P thioester hydrolase family.,
| Target | ACOT4 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 48kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ACOT4. AA range:361-410 |
| Sequence | |
| Specificity | ACOT4 Polyclonal Antibody detects endogenous levels of ACOT4 protein. |
| Gene Name | ACOT4 |
| Protein Name | Acyl-coenzyme A thioesterase 4 |
| Other Name | ACOT4; / PTE2B; / PTEIB; / Acyl-coenzyme A thioesterase 4; / Acyl-CoA thioesterase 4; / PTE-2b; / Peroxisomal acyl coenzyme A thioester hydrolase Ib; / Peroxisomal long-chain acyl-CoA thioesterase Ib; / PTE-Ib |
| Species | Human |
| Gene ID-1 | 122970 |
| Uniprot | Q8N9L9, |
| Species.1 | Mouse |
| Gene ID-2 | |
| Uniprot.1 | Q8BWN8 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate.,function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.,similarity:Belongs to the C/M/P thioester hydrolase family., |
| Cellular Localization | Peroxisome . |
| Tissue Expression | Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle. |
| Signaling_pathway | |
| Research Areas | >>Fatty acid elongation; / >>Biosynthesis of unsaturated fatty acids; / >>Metabolic pathways; / >>Ovarian steroidogenesis |
| Function | Catalytic activity:Palmitoyl-CoA + H(2)O = CoA + palmitate.,Function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.,similarity:Belongs to the C/M/P thioester hydrolase family., |
| RRID |
