SKU: WP12152 Categories: ,

eIF5A2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12152-100
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Product details

Background:

function:The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond., PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine)., similarity:Belongs to the eIF-5A family., tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.,

Specifications

Size50μL/100μL
TargeteIF5A2
ReactivityHuman, Mouse
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)17kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human eIF5A2. AA range:78-127
SpecificityeIF5A2 Polyclonal Antibody detects endogenous levels of eIF5A2 protein.
Gene NameEIF5A2
Protein NameEukaryotic translation initiation factor 5A-2
Other NameEIF5A2; / Eukaryotic translation initiation factor 5A-2; / eIF-5A-2; / eIF-5A2; / Eukaryotic initiation factor 5A isoform 2
SpeciesHuman
Gene ID56648
UniprotQ9GZV4,
Species.1Mouse
Gene ID.1208691
Uniprot.1Q8BGY2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm . Nucleus . Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side . Nucleus, nuclear pore complex . Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. .
Tissue ExpressionExpressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.
Signaling_pathway
Research Areas
FunctionFunction:The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.,PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).,similarity:Belongs to the eIF-5A family.,tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.,
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