SKU: WP0817 Categories: ,

ACSA Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0817-100
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Product details

Background:

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],

Specifications

TargetACSS2
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)77kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 40-120
Sequence
SpecificityACSA Polyclonal Antibody detects endogenous levels of protein.
Gene NameACSS2 ACAS2
Protein NameAcetyl-coenzyme A synthetase, cytoplasmic (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)
Other Name
SpeciesHuman
Gene ID-155902
UniprotQ9NR19,
Species.1Mouse
Gene ID-2
Uniprot.1Q9QXG4
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
BackgroundThis gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
Cellular LocalizationCytoplasm, cytosol .
Tissue ExpressionBlood,Melanoma,Muscle,Platelet,Skin,Tongue,
Signaling_pathway
Research Areas>>Glycolysis / Gluconeogenesis; / >>Pyruvate metabolism; / >>Glyoxylate and dicarboxylate metabolism; / >>Propanoate metabolism; / >>Metabolic pathways; / >>Carbon metabolism
FunctionCatalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,Function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,
RRID
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