SKU: WP10940 Categories: ,

Actin-κ Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10940-100
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Product details

Background:

function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells., miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility., similarity:Belongs to the actin family., subunit:Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others (By similarity). Interacts with PFN1 and PFDN1.,

Specifications

Size50μL/100μL
TargetActin-κ
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)40kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ACTBL2. AA range:81-130
SpecificityActin-κ Polyclonal Antibody detects endogenous levels of Actin-κ protein.
Gene NameACTBL2
Protein NameBeta-actin-like protein 2
Other NameACTBL2; / Beta-actin-like protein 2; / Kappa-actin
SpeciesHuman
Gene ID345651
UniprotQ562R1,
Species.1Mouse
Gene ID.1238880
Uniprot.1Q8BFZ3
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton .
Tissue ExpressionEndometrial tumor,Hepatoma,
Signaling_pathway
Research Areas
FunctionFunction:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the actin family.,subunit:Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others (By similarity). Interacts with PFN1 and PFDN1.,
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