SKU: WM1283 Categories: ,

Actin, Muscle Specific [ABT-MSA] Mouse mAb

Price range: $268.00 through $328.00

SKU: WM1283-50
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Product details

Background:
Actin is a a highly conserved cytoskeletal protein, which contains 6 isoformes, of which 4 are muscle tissue specific: α- skeletal muscle actin, α- cardiac muscle actin, α- smooth muscle actin, γ- Smooth muscle actin. Muscle actin is expressed in skeletal muscle, cardiac and smooth muscle, and muscle derived tumors such as leiomyoma and rhabdomyosarcoma. It is usually not expressed in endothelial cells, connective tissue, melanoma, lymphoma and non myogenic sarcoma.

Specifications

Specification50μL;100μL
TargetActin_Muscle Specific
ReactivityHuman, Mouse, Rat, Monkey, Bovin, Pig, Chick
ApplicationsIHC, WB, IF, ELISA
MW(Calculated)
MW(Observed)42kD
Host SpeciesMouse
IsotypeIgG1, Kappa
Conjugate
ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1000;WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000
CompositionPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Purification ProcessProtein G
Puity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberABT-MSA
ImmunogenSynthesized peptide derived from human Actin, Muscle Specific AA range: 2-50
Sequence
SpecificityThe antibody can specifically recognize proteins from smooth muscle, myocardium and skeletal muscle α actin and smooth muscle derived γ actin, and β actin or non smooth muscle derived γ actin does not respond.
Gene NameActin, Muscle Specific
Protein NameActin, Muscle Specific
AliasActin, alpha cardiac muscle 1;Alpha-cardiac actin;Actin, alpha skeletal muscle;Alpha-actin-1;Actin, gamma-enteric smooth muscle;Alpha-actin-3;Gamma-2-actin;Smooth muscle gamma-actin
Organism-1Human
Gene ID-1
SwissProt-1P68032;P68133;P63267;P62736
Organism-2
Gene ID-2
SwissProt-2
Organism-3
Gene ID-3
SwissProt-3
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCytoplasmic
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