SKU: WP10944 Categories: ,

ACYP2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10944-100
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Product details

Background:

Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016],

Specifications

TargetACYP2
ReactivityHuman, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)18kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from ACYP2 . at AA range: 40-120
Sequence
SpecificityACYP2 Polyclonal Antibody detects endogenous levels of ACYP2 protein.
Gene NameACYP2
Protein NameAcylphosphatase-2
Other NameACYP2; / ACYP; / Acylphosphatase-2; / Acylphosphatase; / muscle type isozyme; / Acylphosphate phosphohydrolase 2
SpeciesHuman
Gene ID-198
UniprotP14621,
Species.1Mouse
Gene ID-2
Uniprot.1P56375,
Species.2Rat
Gene ID-3
Uniprot.2P35745
Organism-4
Gene ID-4
SwissProt-4
BackgroundAcylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016],
Cellular Localizationmitochondrion,
Tissue ExpressionHeart,Muscle,Ovary,
Signaling_pathway
Research Areas>>Pyruvate metabolism; / >>Metabolic pathways
FunctionCatalytic activity:An acylphosphate + H(2)O = a carboxylate + phosphate.,Function:Its physiological role is not yet clear.,similarity:Belongs to the acylphosphatase family.,similarity:Contains 1 acylphosphatase-like domain.,
RRID
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