Name: ADA23 Polyclonal Antibody
SKU: WP0831
Price: 268 USD
Availability: InStock

ADA23 Polyclonal Antibody

Ucallm_WP0831-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP0831-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

ADAM metallopeptidase domain 23(ADAM23) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013],

Specifications

Target	ADA23
Reactivity	Human, Mouse
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	91kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 720-800
Sequence
Specificity	ADA23 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	ADAM23 MDC3
Protein Name	Disintegrin and metalloproteinase domain-containing protein 23 (ADAM 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3)
Other Name
Species	Human
Gene ID-1	8745
Uniprot	O75077,
Species.1	Mouse
Gene ID-2
Uniprot.1	Q9R1V7
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	ADAM metallopeptidase domain 23(ADAM23) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013],
Cellular Localization	Cell membrane; Single-pass type I membrane protein .; [Isoform Gamma]: Secreted.
Tissue Expression	Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.
Signaling_pathway
Research Areas
Function	developmental stage:Highly expressed in the fetal brain.,Domain:A conserved motif AVN[ED]CD within the disintegrin-like domain could be involved in the binding to the integrin receptor.,Function:May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,subunit:Ligand for integrin alpha-V/beta-3.,tissue specificity:Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.,
RRID