SKU: WP0834 Categories: ,

ADA30 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0834-100
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Product details

Background:

ADAM metallopeptidase domain 30(ADAM30) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats. [provided by RefSeq, Jul 2008],

Specifications

TargetADA30
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)86kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 400-480
Sequence
SpecificityADA30 Polyclonal Antibody detects endogenous levels of protein.
Gene NameADAM30 UNQ2509/PRO5997
Protein NameDisintegrin and metalloproteinase domain-containing protein 30 (ADAM 30) (EC 3.4.24.-)
Other Name
SpeciesHuman
Gene ID-111085
UniprotQ9UKF2
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
BackgroundADAM metallopeptidase domain 30(ADAM30) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats. [provided by RefSeq, Jul 2008],
Cellular LocalizationLate endosome membrane; Single-pass type I membrane protein .
Tissue ExpressionExpressed in brain neurons (at protein level) (PubMed:27333034). Expressed in testis (PubMed:10512762).
Signaling_pathway
Research Areas
Functioncofactor:Binds 1 zinc ion per subunit.,Domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,Function:May be involved in spermatogenesis and fertilization.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,tissue specificity:Expressed specifically in testis.,
RRID
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