Name: ADH1G rabbit pAb
SKU: WP4197
Price: 268 USD
Availability: InStock

ADH1G rabbit pAb

Ucallm_WP4197-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP4197-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	ADH1G
Reactivity	Human
Applications	WB
MW(Calculated)	41kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human ADH1G AA range: 185-235
Specificity	This antibody detects endogenous levels of ADH1G at Human
Gene Name	ADH1C ADH3
Protein Name	ADH1G
Other Name
Species	Human
Gene ID	126
Uniprot	P00326
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm.
Tissue Expression
Signaling_pathway
Research Areas	>>Glycolysis / Gluconeogenesis; / >>Fatty acid degradation; / >>Tyrosine metabolism; / >>Pyruvate metabolism; / >>Retinol metabolism; / >>Metabolism of xenobiotics by cytochrome P450; / >>Drug metabolism - cytochrome P450; / >>Metabolic pathways; / >>Alcoholic liver disease
Function	Catalytic activity:An alcohol + NAD(+) = an aldehyde or ketone + NADH.,cofactor:Binds 2 zinc ions per subunit.,miscellaneous:There are 7 different ADH's isozymes in human: three belongs to class-I: alpha, beta, and gamma, one to class-II: pi, one to class-III: chi, one to class-IV: ADH7 and one to class-V: ADH6.,polymorphism:Three alleles are known: ADH1B1 (ADH21) corresponding to variant beta-1, ADH1B2 (ADH22) corresponding to variant beta-2, ADH1B3 (ADH23) corresponding to variant beta-3. The sequence shown is that of allele ADH1B1. The ADH1B2 allele frequency in orientals is approximately 75%, whereas it is less than 5% in most Caucasian populations.,polymorphism:Two main alleles are known, ADH31 or gamma-1 has Arg-272/Ile-350 while ADH32 or gamma-2 has Gln-272/Val-350. ADH31 is associated with a fast rate of ethanol oxidation and ADH32 with a slow rate.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family.,subunit:Dimer of identical or non-identical chains of three types; alpha, beta and gamma.,