ADHFE1 rabbit pAb
Ucallm_WP7472-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ADHFE1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 51kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ADHFE1 |
| Specificity | This antibody detects endogenous levels of ADHFE1 at Human, Mouse,Rat |
| Gene Name | ADHFE1 HMFT2263 |
| Protein Name | Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase) |
| Other Name | |
| Species | Human |
| Gene ID | 137872 |
| Uniprot | Q8IWW8, |
| Species.1 | Mouse |
| Gene ID.1 | 76187 |
| Uniprot.1 | Q8R0N6, |
| Species.2 | Rat |
| Gene ID.2 | 362474 |
| Uniprot.2 | Q4QQW3 |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | Only expressed in adult liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities. |
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