ADO rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ADO |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 30kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ADO |
| Specificity | This antibody detects endogenous levels of ADO at Human, Mouse |
| Gene Name | ADO C10orf22 |
| Protein Name | 2-aminoethanethiol dioxygenase (Cysteamine dioxygenase) |
| Other Name | |
| Species | Human |
| Gene ID | 84890 |
| Uniprot | Q96SZ5, |
| Species.1 | Mouse |
| Gene ID.1 | 211488 |
| Uniprot.1 | Q6PDY2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate . Catalyzes the oxidation of cysteamine (2-aminoethanethiol) to hypotaurine . Catalyzes the oxidation of regulators of G-protein signaling 4 (RGS4) and 5 (RGS5) and interleukin-32 (IL32) . |
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