Product details
Background:
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ADX rabbit pAb
Ucallm_WP17936-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FDX1 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, WB |
| MW(Calculated) | 20kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human N-ternal ADX |
| Specificity | This antibody detects endogenous levels of ADX at Human, Mouse,Rat |
| Gene Name | FDX1 ADX |
| Protein Name | Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin) |
| Other Name | Adrenodoxin, mitochondrial; / Adrenal ferredoxin; / Ferredoxin-1; / Hepatoredoxin |
| Species | Human |
| Gene ID | 2230 |
| Uniprot | P10109, |
| Species.1 | Mouse |
| Gene ID.1 | 14148 |
| Uniprot.1 | P46656, |
| Species.2 | Rat |
| Gene ID.2 | 29189 |
| Uniprot.2 | P24483 |
| Cellular Localization | Mitochondrion matrix . |
| Tissue Expression | Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Essential for the synthesis of various steroid hormones . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis . Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity). |
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