Product details
Background:
AF1L1 rabbit pAb
Ucallm_WP3732-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AF1L1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AF1L1 AA range: 180-230 |
| Specificity | This antibody detects endogenous levels of AF1L1 at Human/Mouse/Rat |
| Gene Name | AFAP1L1 |
| Protein Name | AF1L1 |
| Other Name | Actin filament-associated protein 1-like 1; / AFAP1-like protein 1 |
| Species | Human |
| Gene ID | 134265 |
| Uniprot | Q8TED9, |
| Species.1 | Mouse |
| Gene ID.1 | 106877 |
| Uniprot.1 | Q8BZI0, |
| Species.2 | Rat |
| Gene ID.2 | 291565 |
| Uniprot.2 | D4AB98 |
| Cellular Localization | Cytoplasm . Cell projection, podosome . Cell projection, invadopodium . Cytoplasm, cytoskeleton, stress fiber . |
| Tissue Expression | Expressed in breast, colon and brain. In all 3 tissues, expressed in the microvasculature (at protein level). In addition, in the breast, found in the contractile myoepithelial cell layer which surrounds the breast ducts (at protein level). In the colon, expressed in the mucous membrane and colonic crypts and in the smooth muscle cell layer which provide movement of the colon (at protein level). In the cerebellum, localized around the Purkinje neurons and the granule cells of the granular layer, but not inside cell bodies (at protein level). Outside of the cerebellar cortex, expressed in glial cells (at protein level). Highly expressed away from the cell bodies within the dentate nucleus (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 PH domains., |
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