AFG3L2 Polyclonal Antibody
Ucallm_WP16001-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | AFG3L2 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 88kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:10000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AFG3L2. at AA range: 744-793 |
| Specificity | AFG3L2 Polyclonal Antibody detects endogenous levels of AFG3L2 |
| Gene Name | AFG3L2 |
| Protein Name | AFG3L2 |
| Other Name | AFG3-like protein 2; / Paraplegin-like protein |
| Species | Human |
| Gene ID | 10939 |
| Uniprot | Q9Y4W6, |
| Species.1 | Mouse |
| Gene ID.1 | 69597 |
| Uniprot.1 | Q8JZQ2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion . Mitochondrion inner membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitous. Highly expressed in the cerebellar Purkinje cells. |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia |
| Research Areas | >>Spinocerebellar ataxia |
| Function | cofactor:Binds 1 zinc ion per subunit .,Function:Putative ATP-dependent protease.,similarity:In the C-terminal section; belongs to the peptidase M41 family.,similarity:In the N-terminal section; belongs to the AAA ATPase family.,tissue specificity:Ubiquitous., |
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