Name: AK6 Polyclonal Antibody
SKU: WP10990
Price: 268 USD
Availability: InStock

Product details

Background:

adenylate kinase 6(AK6) Homo sapiens This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

Specifications

Size	50μL/100μL
Target	AK6
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	20kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human KAD6. AA range:11-60
Specificity	AK6 Polyclonal Antibody detects endogenous levels of AK6 protein.
Gene Name
Protein Name	Adenylate kinase isoenzyme 6
Other Name	TAF9; / AK6; / CINAP; / AD-004; / CGI-137; / Adenylate kinase isoenzyme 6; / ATP-AMP transphosphorylase 6; / Coilin-interacting nuclear ATPase protein; / hCINAP
Species	Human
Gene ID	6880
Uniprot	Q9Y3D8,
Species.1	Mouse
Gene ID.1	108143
Uniprot.1	Q8VCP8,
Species.2	Rat
Gene ID.2	373541
Uniprot.2	Q5EB68
Cellular Localization	Nucleus, nucleoplasm. Nucleus, Cajal body. Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
Tissue Expression	Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, chorionic villi and the central nervous system.
Signaling_pathway
Research Areas	>>Purine metabolism; / >>Metabolic pathways; / >>Nucleotide metabolism; / >>Biosynthesis of cofactors; / >>Ribosome biogenesis in eukaryotes
Function	regulation of cell growth, chromatin organization, transcription, transcription, DNA-dependent, transcription initiation,RNA elongation, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, transcription initiation from RNA polymerase II promoter,RNA elongation from RNA polymerase II promoter, protein complex assembly, protein amino acid acetylation,regulation of cell size, positive regulation of biosynthetic process, regulation of catabolic process, negative regulation of catabolic process, response to organic substance, regulation of specific transcription from RNA polymerase II promoter, positive regulation of specific transcription from RNA polymerase II promoter, positive regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, positive regulation of gene expression, regulation of cell death, chromatin modification, covalent chromatin modification, histone modification, histone acetylation, regulation of proteolysis,positive regulation of cell growth, positive regulation of cellular biosynthetic process, regulation of cellular catabolic process, negative regulation of cellular catabolic process, regulation of cellular protein metabolic process, negative regulation of cellular protein metabolic process, regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, regulation of cellular component size, regulation of gene-specific transcription, RNA biosynthetic process, response to cytokine stimulus,cellular response to DNA damage stimulus, regulation of growth, regulation of protein catabolic process, negative regulation of protein catabolic process, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, positive regulation of gene-specific transcription, protein amino acid acylation, macromolecular complex subunit organization, histone H3 acetylation,regulation of transcription, positive regulation of cell size, negative regulation of proteolysis, positive regulation of transcription, DNA-dependent, positive regulation of growth, positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, positive regulation of transcription, positive regulation of transcription from RNA polymerase II promoter, positive regulation of response to stimulus, positive regulation of nitrogen compound metabolic process, negative regulation of protein metabolic process, regulation of RNA metabolic process, positive regulation of RNA metabolic process, chromosome organization, negative regulation of cell death, regulation of response to cytokine stimulus, positive regulation of response to cytokine stimulus, macromolecular complex assembly, protein complex biogenesis, response to interleukin-1,

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AK6 Polyclonal Antibody

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AK6 Polyclonal Antibody

Product details

Specifications

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