Product details
Background:
AMPL rabbit pAb
Ucallm_WP4657-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AMPL |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 57kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AMPL AA range: 332-382 |
| Specificity | This antibody detects endogenous levels of AMPL at Human/Mouse/Rat |
| Gene Name | LAP3 LAPEP PEPS |
| Protein Name | AMPL |
| Other Name | |
| Species | Human |
| Gene ID | 51056 |
| Uniprot | P28838, |
| Species.1 | Mouse |
| Gene ID.1 | 66988 |
| Uniprot.1 | Q9CPY7, |
| Species.2 | Rat |
| Gene ID.2 | 289668 |
| Uniprot.2 | Q68FS4 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Arginine and proline metabolism; / >>Glutathione metabolism; / >>Metabolic pathways |
| Function | Catalytic activity:Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.,Catalytic activity:Release of N-terminal proline from a peptide.,cofactor:Binds 2 zinc ions per subunit. One zinc ion is tightly bound and essential for enzyme activity, while the second metal coordination site can be occupied by zinc, magnesium or manganese to give enzymes of different activities.,Function:Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.,similarity:Belongs to the peptidase M17 family.,subunit:Homohexamer., |
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