SKU: WP6167 Categories: ,

ANKRD2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6167-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetANKRD2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)40kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ANKRD2
SpecificityThis antibody detects endogenous levels of ANKRD2 at Human, Mouse
Gene NameANKRD2 ARPP
Protein NameAnkyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp)
Other Name
SpeciesHuman
Gene ID26287
UniprotQ9GZV1,
Species.1Mouse
Gene ID.156642
Uniprot.1Q9WV06
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, myofibril, sarcomere, I band . Cytoplasm, cytosol. Nucleus. Nucleus, PML body. In the sarcoplasm of differentiated striated muscle cells, where it is cytosolic and enriched in the I band. In nucleus and PML bodies of proliferating and undifferentiated myoblasts. Associates with the euchromatin in the nucleus of myocytes upon muscle stress.
Tissue ExpressionMostly expressed in skeletal and cardiac muscles. Found in slow fibers. Also expressed in kidney, but to a lower extent (at protein level).
Signaling_pathway
Research Areas
FunctionFunctions as a negative regulator of myocyte differentiation. May interact with both sarcoplasmic structural proteins and nuclear proteins to regulate gene expression during muscle development and in response to muscle stress.
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