SKU: WP6518 Categories: ,

EPHX2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6518-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetEPHX2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)61kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human EPHX2
SpecificityThis antibody detects endogenous levels of EPHX2 at Human, Mouse,Rat
Gene NameEPHX2
Protein NameBifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (CEH) (Epoxide hydratase) (Soluble epoxide hydrolase) (SEH); Lipid-phosphate phosphatase (EC 3.1.3.76)]
Other Name
SpeciesHuman
Gene ID2053
UniprotP34913,
Species.1Mouse
Gene ID.113850
Uniprot.1P34914,
Species.2Rat
Gene ID.265030
Uniprot.2P80299
Cellular LocalizationCytoplasm. Peroxisome.
Tissue Expression
Signaling_pathwayCellular Processes >> Transport and catabolism >> Peroxisome
Research Areas
FunctionBifunctional enzyme . The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides . Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady-state levels of physiological mediators .; Bifunctional enzyme . The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid . Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates .
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