ANR11 rabbit pAb
Ucallm_WP3810-50
Price range: $268.00 through $328.00
Product details
Background:
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012],
Specifications
| Size | 50μL/100μL |
| Target | ANR11 |
| Reactivity | Human, Mouse |
| Applications | IHC, IF |
| MW(Calculated) | 293kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ANR11 AA range: 557-607 |
| Specificity | This antibody detects endogenous levels of ANR11 at Human |
| Gene Name | ANKRD11 ANCO1 |
| Protein Name | ANR11 |
| Other Name | |
| Species | Human |
| Gene ID | 29123 |
| Uniprot | Q6UB99 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Localizes to chromatin during prometaphase. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation.,sequence Caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 4 ANK repeats.,subunit:Interacts with the PAS region of the p160 coactivators., |
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